Methods for identifying and mapping recent segmental and gene duplications in eukaryotic genomes.

نویسندگان

  • Razi Khaja
  • Jeffrey R MacDonald
  • Junjun Zhang
  • Stephen W Scherer
چکیده

The aim of this chapter is to provide instruction for analyzing and mapping recent segmental and gene duplications in eukaryotic genomes. We describe a bioinformatics-based approach utilizing computational tools to manage eukaryotic genome sequences to characterize and understand the evolutionary fates and trajectories of duplicated genes. An introduction to bioinformatics tools and programs such as BLAST, Perl, BioPerl, and the GFF specification provides the necessary background to complete this analysis for any eukaryotic genome of interest.

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عنوان ژورنال:
  • Methods in molecular biology

دوره 338  شماره 

صفحات  -

تاریخ انتشار 2006